![]() ![]() For dogs over 100 pounds give the appropriate combination of tablets. The usual dose of Sentinel for dogs 2 to 10 pounds is 2.3mg/46mg, 11 to 25 pounds is 5.75mg/115mg, 26 to 50 pounds is 11.5mg/230mg and 51 to 100 pounds is 23mg/460mg given once a month year-round. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. How should this medication be given: Give Sentinel exactly as directed by the veterinarian. What should I discuss with my veterinarian before giving Sentinel to my pet: Tell your veterinarian if your pet has ever had an allergic reaction to the medication. Sentinel may also be used for purposes other than those listed in this guide. The American Heartworm Society recommends that heartworm prevention be used year-round. Sentinel is also used to control fleas by preventing the development of flea eggs. Sentinel also protects against hookworms, roundworms, and whipworms. What is Sentinel: Sentinel is given once a month for the prevention of heartworm disease in dogs. This medication should be given once a month year-round. Sentinel is available as artificial beef flavored (derived from pork and soy protein) chewable tablets. What is the most important information I should know about Sentinel: Sentinel is a medication FDA-approved for use in dogs. Milbemycin Oxime (mil’-beh-my’-sin ox’-eem) and Lufenuron (lew-fen’-your-on) ![]() Consult your veterinarian for pregnant or lactating dogs. To prevent re-infection, clean up stools on a daily basis. ![]() Its also important to eliminate fleas and to not feed your pet uncooked meat or fish. Its important to maintain good personal hygiene, since humans can contract hookworms and roundworms. If these or other symptoms develop contact your veterinarian. Side effects are rare, though some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, or seizures. Sentinel may be given along with Capstar, which treats flea infestation. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Sentinel is the only monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Keep this and all drugs out of the reach of children.Sentinel Spectrum Medium Dogs 26-50 lbs (11-22 kg) Chews 3 Pack Studies have been performed with milbemycin oxime and lufenuron alone. The safety of this medication has not been evaluated in dogs used for breeding or in lactating females. Do not use in dogs or puppies less than two pounds of body weight. Do not use in puppies less than six weeks of age. These reactions are presumably caused by release of protein from dead or dying microfilariae. Mild, transient hypersensitivity reactions, such as labored breathing, vomiting, hypersalivation, and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. This medication is not effective against adult D. At the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms. Prior to administration of Sentinel Spectrum, dogs should be tested for existing heartworm infections. Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. ![]()
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